Iron Deficiency in Patients with Idiopathic Pulmonary Arterial Hypertension (iPAH)

Intravenous iron therapy in patients with idiopathic pulmonary arterial hypertension and iron deficiency.

UNLABELLED In patients with idiopathic pulmonary arterial hypertension (iPAH), iron deficiency is common and has been associated with reduced exercise capacity and worse survival. Previous studies have shown beneficial effects of intravenous iron administration. In this study, we investigated the use of intravenous iron therapy in iron-deficient iPAH patients in terms of safety and effects on e...

Unexplained iron deficiency in idiopathic and heritable pulmonary arterial hypertension.

BACKGROUND Anaemia is common in left heart failure and is associated with a poorer outcome. Many patients with pulmonary arterial hypertension (PAH) are anaemic or iron-deficient. This study was performed to investigate the prevalence of iron deficiency in PAH and to identify possible causes. METHODS All patients with idiopathic or heritable PAH diagnosed in 1995-2008 were identified. Control...

Iron deficiency is common in idiopathic pulmonary arterial hypertension.

The aims of this study were to assess the prevalence of iron deficiency in idiopathic pulmonary arterial hypertension (IPAH) and investigate whether oral iron supplementation has effects in iron-deficient patients. Iron parameters were measure for all IPAH patients attending our centre (VU University Medical Center, Amsterdam, the Netherlands) between May 2009 and February 2010. Iron data were ...

Prognostic Value of Blood Gas Analyses in Patients with Idiopathic Pulmonary Arterial Hypertension Running title: Blood gases in IPAH

idiopathic pulmonary arterial hypertension

cytometry analysis of BAL cells. Table 1 integrates information given in our published paper, clearly demonstrating that the number of BAL neutrophils was fair in our case series. This unfortunately prevented a definitive evaluation of whether polymorph nucleates represent a source of IL-17. Nonetheless, as shown in figure 1, in selected cases with a significant number of BAL neutrophils (two s...